August 10, 2022
Dr. Sintim’s lab in the Institute of Drug Discovery at Purdue University and the Bindley Bioscience Center Purdue Proteomics Facility (PPF) have published their research in the Journal “Molecules”
Millions of drug-resistant infections are reported annually in the U.S., with fatalities well over 30,000, and billions of dollars used annually in the treatment of such infections. The overuse of traditional antibiotics and slow introduction of new classes of antibacterial agents have contributed to the rising incidences of multidrug-resistant bacterial infections. A new paper from Sintim lab at the Purdue University's Institute for Drug Discovery in collaboration with the Purdue Proteomics Facility identifies a new class of alkynyl isoquinoline compounds with strong antibacterial activity against plethora of Gram-positive bacteria including Staphylococcus aureus. The finding was recently published in the journal "Molecules"
